| |
Kacar B and Gaucher EA Experimental evolution of protein interaction networks Biochem J, In press. |
|
| |
Cacan, E.*, Kratzer, J. T.*, Cole, M. F., and E. A. Gaucher. Interchanging functionality among homologous elongation factors using signatures of heterotachy. Journal of molecular evolution, 2013. 76(1-2): p. 4-12. |
 |
 |
Kacar B and Gaucher EA Towards the Recapitulation of Ancient History in the Laboratory: Combining Synthetic Biology with Experimental Evolution Artificial Life pp. 11-18. 2012. |
Abstract |
|
Zhao ZM, Reynolds AB, Gaucher EA. The evolutionary history of the catenin gene family during metazoan evolution, BMC Evol. Bio. Epub 2011, 'Highly Accessed.' |
|
| |
Cole, MF, Gaucher EA. Utilizing natural diversity to evolve protein function: Applications towards thermostability
Current Opinions in Chemical Biology, in press 2011 |
|
| |
Perez-Jimenez R, Inglés-Prieto A, Zhao Z-M, Sanchez-Romero I, Alegre-Cebollada J, Kosuri P, Garcia-Manyes S, Kappock TJ, Tanokura M, Holmgren A, Sanchez-Ruiz JM, Gaucher EA, Fernandez JM. Single-molecule paleoenzymology probes the chemistry of resurrected enzymes. Nat. Struct. & Mol. Bio., 18(4): 592-6. Epub 2011. |
|
| |
Carnahan R.H., Rockas A, Gaucher E.A., Reynolds A.B. The molecular evolution of the p120-catenin subfamily and its functional associations. PLoS One. 2010 Dec 31;5(12):e15747. |
|
|
Cole M.F., Gaucher E.A (2010). Exploiting models of molecular evolution to efficiently direct protein engineering. J Mol Evol. Epub |
|
 |
Chen F, Gaucher E.A., Leal N.A., Hutter D., Havemann S.A., Govindarajan S., Ortlund E.A., S.A Benner (2010). Reconstructed evolutionary adaptive paths give polymerases accepting reversible terminators for sequencing and SNP detection.
Proc Natl Acad Sci U S A. 107(5):1948-53. |
|
| Johnson, R. J., Gaucher, E. A., Sautin, Y. Y., Henderson, G. N., Angerhofer, A. J., and S. A. Benner (2008). The planetary biology of ascorbate and uric acid and their relationship with the epidemic of obesity and cardiovascular disease. Med Hypotheses. 71:22-31. |
|
| Gaucher, E. A., Ganesh, O. & S. Govindarajan (2008). Paleotemperature trend for Precambrian life inferred from resurrected proteins. Nature, 451: 704-707. |
|
| Benner, S. A., Sassi, S., and E. A. Gaucher (2007). Molecular Paleoscience. Systems Biology from the Past. Adv. Enzymol. Relat. Areas Mol. Biol. 75:1-132. |
|
| Gaucher, E. A., De Kee, D. W., and S. A. Benner (2006) Application of DETECTER, an evolutionary genomic tool to analyze genetic variation, to the cystic fibrosis gene family. BMC Genomics 7:44. |
|
|
Li, T., Chamberlin, S. G., Caraco M. D., Gaucher, E. A., Liberles, D. A., and S. A. Benner (2006). Transition redundant approach-to-equilibrium analysis of gene sequences: Tools to date events in the genomic record. BMC Evol. Biol. 6:25. |
|
|
Phillips, S. E., Vincent, P., Rizzieri, K. E., Schaaf, G., Bankaitis, V. A., and E. A. Gaucher (2006). The diverse biological functions of phosphatidylinositol transfer proteins in eukaryotes. Crit. Rev. Biochem. Mol. Biol. 41:21-49. |
|
|
Gaucher, E. A. and M. Miyamoto (2005). A call for likelihood phylogenetics even when evolution is heterogeneous. Molecular Phylogenetics & Evolution 37:928-931. |
|
|
Thomson, J. M., Gaucher, E. A., Burgan, M. F., Li, T., Aris, J. P. and S. A. Benner (2005). Resurrecting ancient alcohol dehydrogenases from Yeast. Nature Genetics 37:630-635. |
|
|
Gaucher, E. A., Graddy, L. G., Simmen, R. C. M., Simmen, F. A., Kowalski, A. A., Schreiber, D. R., Liberles, D. A., Zhao, G., Janis, C. M. and S. A. Benner (2004). The planetary biology of aromatases in pigs. BMC Biology. 2(1):19. |
|
|
West, C. M., Van Der Wel, H., Sassi, S. and E. A. Gaucher. Cytoplasmic glycosylation of protein-hydroxyproline and its relationship to other glycosylation pathways. Biochim. Biophys. Acta. 1673:29-44. |
|
|
Gaucher, E. A., Burgan, M. F., Thomson, J. M. and S. A. Benner (2003). Inferring the paleoenvironment of ancient bacteria based on resurrected ancestral proteins. Nature 425:285-288. |
|
|
Gaucher, E. A., Miyamoto, M. M. and S. A. Benner (2003). Evolutionary, structural and biochemical evidence for a new interaction site of the leptin obesity protein. Genetics 163:1549-1553. |
|
|
Gaucher, E. A, Gu, X., Miyamoto, M. M. and S. A. Benner (2002). Predicting functional divergence in protein evolution by site-specific rate shifts. Trends Biochem. Sci. 27:315-321. |
|
|
Benner, S. A., Caraco, M. D., Thomson, J. M. and E. A. Gaucher (2002). Planetary biology - paleontological, geological, and molecular histories of life. Science 296:864-868. |
|
|
West, C. M., van der Wel, H. and E.A. Gaucher (2002). Complex glycosylation of Skp1 in Dictyostelium: implications for the modification of other eukaryotic cytoplasmic and nuclear proteins. Glycobiology 12:17R-27R. |
|
|
Gaucher, E. A., Das, U. K., Miyamoto, M. M. and S. A. Benner (2002). The Crystal Structure of eEF1A Supports the Functional Predictions of an Evolutionary Analysis of Rate Changes among Elongation Factors. Mol. Biol. Evol. 19:569-573. |
|
|
Gaucher, E. A., Miyamoto, M. M. and S. A. Benner (2001). Function-structure analysis of proteins using covarion-based evolutionary approaches: Elongation factors. Proc. Nat. Acad. Sci. 98:548-552. |
|
|
Laten, H. M., Majumdar, A. and E. A. Gaucher (1998). SIRE-1, a copia/Ty1-like retroelement from soybean, encodes a retroviral envelope-like protein. Proc. Nat. Acad. Sci. 95:6897-6902. |
|
